The advantages of infrared protein analysis are its ease of use and its relatively inexpensive capability of studying proteins in aqueous media at any buffer conditions. The CONFOCHECK is a dedicated Fourier transform infrared (FTIR) spectrometer system that was developed to fulfill the demanding requirements for protein analysis in aqueous solution. Its specific concept facilitates a fast data acquisition with a high sample throughput controlled by a user friendly software interface.
Protein dynamics (temperature induced conformational changes)
Protein quantification (from 0.03 mg/ml up to > 100mg/ml in aqueous solution)
Determination of secondary structure
Monitoring of conformational changes during protein aggregation, precipitation and crystallization
Quantification of all kind of solutes in aqueous samples